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Pulmonology
Change in management and outcome of mechanical ventilation in Korea: a prospective observational study
Jae Kyeom Sim, Sang-Min Lee, Hyung Koo Kang, Kyung Chan Kim, Young Sam Kim, Yun Seong Kim, Won-Yeon Lee, Sunghoon Park, So Young Park, Ju-Hee Park, Yun Su Sim, Kwangha Lee, Yeon Joo Lee, Jin Hwa Lee, Heung Bum Lee, Chae-Man Lim, Won-Il Choi, Ji Young Hong, Won Jun Song, Gee Young Suh
Korean J Intern Med. 2022;37(3):618-630. Published online February 11, 2022
Background/Aims: There are few studies describing contemporary status of mechanical ventilation in Korea. We investigated changes in management and outcome of mechanical ventilation in Korea.
Methods: International, prospective observational cohort studies have been conducted every 6 years since 19..
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Cardiology
Long-term outcomes in ST-elevation myocardial infarction patients treated according to hospital visit time
Seok Oh, Dae Young Hyun, Kyung Hoon Cho, Ju Han Kim, Myung Ho Jeong
Korean J Intern Med. 2022;37(3):605-617. Published online November 16, 2021
Background/Aims: Rapid percutaneous coronary intervention (PCI) is the cornerstone of treatment for ST-elevation myocardial infarction (STEMI). However, there have been conflicting results regarding the differences in clinical outcomes between on-hours and off-hours presentation in STEMI patients. W..
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Off-hour presentation and outcomes for percutaneous coronary intervention in acute myocardial infarction with Killip III–IV
Seok Oh, Ju Han Kim, Kyung Hoon Cho, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Youngkeun Ahn, Myung Ho Jeong
Korean J Intern Med. 2022;37(3):591-604. Published online April 28, 2022
Background/Aims: Acute myocardial infarction (AMI) is conventionally recognized as an urgent medical condition requiring timely and effective reperfusion therapy. However, the results of studies on the clinical outcomes in AMI according to hospital visit timings are inconclusive. To explore the differ..
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Gastroenterology
Long-term effect of the eradication of Helicobacter pylori on the hemoglobin A1c in type 2 diabetes or prediabetes patients
Won Seok Kim, Yonghoon Choi, Nayoung Kim, Seon Hee Lim, Gitark Noh, Ki Wook Kim, Jaehyung Park, Hyeongho Jo, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Dong Ho Lee
Korean J Intern Med. 2022;37(3):579-590. Published online January 7, 2022
Background/Aims: The long-term effect of Helicobacter pylori eradication on the metabolic syndrome or diabetes are unclear. The aim of this study was to evaluate the effect of H. pylori eradication on glycemic control in type 2 diabetes mellitus (T2DM) or prediabetes mellitus (preDM).
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Radiology plus ileocolonoscopy versus radiology alone in Crohn’s disease: prognosis prediction and mutual agreement
Hye Kyung Hyun, Jongwook Yu, Eun Ae Kang, Jihye Park, Soo Jung Park, Jae Jun Park, Tae Il Kim, Won Ho Kim, Jae Hee Cheon
Korean J Intern Med. 2022;37(3):567-578. Published online October 26, 2021
Background/Aims: The optimal tools for monitoring Crohn’s disease (CD) are controversial. We compared radiology plus ileocolonoscopy and radiology alone in terms of prognosis prediction and evaluated the agreement between radiologic and ileocolonoscopic findings in patients with CD.
Methods: Pati..
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Safety of direct oral anticoagulants compared to warfarin in cirrhotic patients with atrial fibrillation
Seo Yeon Yoo, Eunju Kim, Gi-Byoung Nam, Danbi Lee, Ju Hyun Shim, Kang Mo Kim, Young-Suk Lim, Han Chu Lee, Young-Hwa Chung, Yung Sang Lee, Jonggi Choi
Korean J Intern Med. 2022;37(3):555-566. Published online January 26, 2022
Background/Aims: The safety of direct oral anticoagulants (DOACs) compared with warfarin in patients with both nonvalvular atrial fibrillation (AF) and clinically confirmed liver cirrhosis (LC) has not been well studied. We compared the risk of a major bleeding event between DOAC and warfarin treatm..
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Is radiological healing alone enough? ‘Can’t take my eyes off’ the mucosa
Su Hyun Park, Sang Hyoung Park
Korean J Intern Med. 2022;37(3):551-552. Published online April 28, 2022
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Role of T cells in ischemic acute kidney injury and repair
Kyungho Lee, Hye Ryoun Jang
Korean J Intern Med. 2022;37(3):534-550. Published online April 28, 2022
Ischemic acute kidney injury (AKI) is a common medical problem with significant mortality and morbidity, affecting a large number of patients globally. Ischemic AKI is associated with intrarenal inflammation as well as systemic inflammation; thus, the innate and adaptive immune systems are implicate..
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Omics-based biomarkers for diagnosis and prediction of kidney allograft rejection
Jeong-Hoon Lim, Byung Ha Chung, Sang-Ho Lee, Hee-Yeon Jung, Ji-Young Choi, Jang-Hee Cho, Sun-Hee Park, Yong-Lim Kim, Chan-Duck Kim
Korean J Intern Med. 2022;37(3):520-533. Published online April 15, 2022
Kidney transplantation is the preferred treatment for patients with end-stage kidney disease, because it prolongs survival and improves quality of life. Allograft biopsy is the gold standard for diagnosing allograft rejection. However, it is invasive and reactive, and continuous monitoring is unreal..
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Glomerular filtration rate as a kidney outcome of diabetic kidney disease: a focus on new antidiabetic drugs
Hyo Jin Kim, Sang Soo Kim, Sang Heon Song
Korean J Intern Med. 2022;37(3):502-519. Published online April 4, 2022
Diabetes has reached epidemic proportions, both in Korea and worldwide and is associated with an increased risk of chronic kidney disease and kidney failure (KF). The natural course of kidney function among people with diabetes (especially type 2 diabetes) may be complex in real-world situations. St..
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Emotional and cognitive changes in chronic kidney disease
Duk-Soo Kim, Seong-Wook Kim, Hyo-Wook Gil
Korean J Intern Med. 2022;37(3):489-501. Published online March 8, 2022
Chronic kidney disease (CKD) leads to cognitive impairment and emotional changes. However, the precise mechanism underlying the crosstalk between the kidneys and the nervous system is not fully understood. Inflammation and cerebrovascular disease can influence the development of depression in CKD. C..
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Histological similarity between tubulointerstitial nephritis and salivary gland biopsy in primary Sjögren’s syndrome
Yoon Ji Tak, Jong Sun Kim, Kyung-Ann Lee, Hyun-Sook Kim, So-Young Jin
Korean J Intern Med. 2022;37(2):486-487. Published online October 22, 2021
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Diabetic ketoacidosis and acute pancreatitis in a patient with agenesis of the dorsal pancreas
Chaiho Jeong, Ye Seul Yang, Hyun-Shik Son, Tae-Seo Sohn
Korean J Intern Med. 2022;37(2):484-485. Published online February 16, 2022
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Paradoxical reaction of tuberculosis masquerading as a gastric subepithelial tumor
Jinmo Kim, Kwangwoo Nam, Jooyeop Lee, Jun-Ho Choi, Won-Ae Lee
Korean J Intern Med. 2022;37(2):482-483. Published online November 16, 2021
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Hypervascular hepatic masses in a patient who underwent the Fontan procedure
Min Kyu Kang, Sung Bum Kim, Joon Hyuk Choi
Korean J Intern Med. 2022;37(2):480-481. Published online January 8, 2021
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Cancer risk in Korean patients with gout
Shih-Wei Lai, Chiu-Shong Liu, Bing-Fang Hwang
Korean J Intern Med. 2022;37(2):478-479. Published online October 21, 2021
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Geriatrics
Factors associated with anticholinergic burden among older patients in long-term care hospitals in Korea
Jung-Yeon Choi, Hongsoo Kim, Young-il Jung, Seungyeon Chun, Sooyoung Yoo, Jae-Young Lim, Jin Young Ko, Kayoung Park, Kwang-il Kim
Korean J Intern Med. 2022;37(2):468-477. Published online February 18, 2022
Background/Aims: Drugs with anticholinergic properties (DAPs) are associated with adverse health outcomes in older patients. The objective of this study was to evaluate the factors that determine the prescribing of more DAPs in long-term care hospitals (LTCHs) in Korea. In addition, the current patt..
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Rheumatology
Cancer risk in Korean patients with gout
Yoon-Jeong Oh, Yun Jong Lee, Eunyoung Lee, Bumhee Park, Jae-Woo Kwon, Jeongwon Heo, Ki Won Moon
Korean J Intern Med. 2022;37(2):460-467. Published online March 23, 2021
Background/Aims: Using a nationwide cohort, we investigated the cancer risk in Korean patients with gout.
Methods: Data were obtained from the Korean National Health Insurance Service Database. Patients with gout were defined as those aged ≥ 20 years who were diagnosed with gout and received anti..
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Infectious diseases
Comparison of antibody responses after the 1st and 2nd doses of COVID-19 vaccine with those of patients with mild or severe COVID-19
Hye Hee Cha, So Yun Lim, Ji-Soo Kwon, Ji Yeun Kim, Seongman Bae, Jiwon Jung, Sung-Han Kim
Korean J Intern Med. 2022;37(2):455-459. Published online February 28, 2022
Background/Aims: Data comparing the antibody responses of different coronavirus disease 2019 (COVID-19) vaccine platforms according to dose with natural severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection-induced antibody responses are limited.
Methods: Blood samples from adult p..
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